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Waterfall D-Mannose®

50 x 1000mg Tablets

Waterfall D-Mannose ® Tablet Sachets

If you suffer from bladder pain or urinary tract infections, Waterfall D-Mannose is the fast and all natural way to treat cystitis, prostatitis and UTIs.


Order before 5:30pm for same day dispatch.

Letterbox friendly.

Free email & phone support with product purchase.

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Waterfall D-Mannose Product Awards

Product Information

Gluten Free

Suitable for Vegetarians

Fits through your letterbox

100% Natural & Bioactive DMannose

Discreet Packaging

All Packaging Recyclable

SKU: 5060086380071

Weight: 50 x 1000mg Tablets

Questions? Call +44 01904 789559

How to use D-Mannose Tablets

For Urgent Support

3 x 1000mg tablets every three hours for a couple of days plus a middle of the night dose is a good guide for most people who need urgent support. Reduce slowly as symptoms improve.

Prophylactic Maintenance

2/3 tablets before bed is an excellent prophylactic dose.

For Sex-related Support

2/3 tablets an hour before sex, and immediately afterwards (don't urinate until afterwards). Using for about 48 hours afterwards is an excellent way of preventing further sex-related episodes.

Basically, you take as much of it as you need either for urgent support, or maintenance. Reduce slowly as symptoms improve. Try using before travel, cycling or sport as a preventative.

Seek medical help if symptoms are not improving.

Children: reduce dosage according to age.

Benefits of D-Mannose

  • Stops UTIs and cystitis symptoms, and prevents further infections in both adults and children.
  • Brings rapid relief from the pain, burning, and cramping feelings caused by infections.
  • Provides a safe long-term solution to cystitis problems. People who take Waterfall D-Mannose regularly soon begin to lose the propensity for reinfection. If a new infection threat occurs, immediately taking a double dose of Waterfall D-Mannose stops it in its tracks almost every time.
  • Massively improves the quality of life for cystitis sufferers. By getting rid of the infection problem at source, antibiotics and their toxic side-effects can be avoided.
  • Benefits the kidneys. Customer feedback strongly suggests that Waterfall D-Mannose gradually improves kidney function by about 2% per month for people whose kidneys have been damaged by frequent reinfection and the drugs taken to treat those infections.
  • Stops urinary reflux that can damage the kidneys, by getting rid of the inflammation and bacterial agglomeration that closes up the neck of the bladder.
  • Helps stop incontinence. Often people who are incontinent or intermittently so, have damaged bladders with an ever-present low level of bacteria in the urine, and a slight discomfort which people can become so used to that they no longer notice it. The Waterfall D-Mannose flushes away the bacteria, and also acts as a natural anti-inflammatory. The incontinence often just stops as the bladder returns to normal.
  • Works against bacterial prostatatis. People who have been in pain for years with this problem have reported substantial or complete relief within a matter of two or three days. (Men should ejaculate within a couple of hours of taking the Waterfall D-Mannose to help rid the prostate of mannose-bound bacteria, and the endotoxins that accumulate in the prostate during infection. It may be painful to do this initially, but within two days it should no longer be painful, and this is a sign that things are returning to normal.
  • Normalises and protects the entire urinary system. The longer people continue to take a maintenance dose of Waterfall D-Mannose , the healthier their urinary system becomes.

D-Mannose Customer Reviews

We’ve collected hundreds of stories over the years from our customers by email, some of those can be seen below. As technology has progressed, we now use an independent review company called Reevoo to collect feedback on our behalf. Reevoo have collected hundreds reviews already, and can be seen here.

Kat - Cranberry Pills

... I couldn't believe it, all my symptoms cleared up in a week. I am now on one maintenance dose before I go to bed at night...
Kat Whelan - email

Kelly - Cystitis since I was 16

... I have using Waterfall D-Mannose for the past 6 weeks and It has really been a miracle. I feel so much better and now able to get on with my life...
Kelly - email

Reevoo Reviews

D-Mannose Side Effects / Drug Interactions

None known. Used by pregnant women, small children, diabetics, and all animals.

A recent clinical trial researching long term DMannose use in 60 participants found no side effects:

Total, serious adverse events: # participants affected / at risk = 0/60 (0.00%)
Total, other (not including serious) adverse events: # participants affected / at risk 0/60 (0.00%)
Daniele Porru, IRCCS Policlinico S. Matteo - D Mannose in Recurrent Urinary Tract Infections (Clinical Trial)


Each tablet contains: 1000mg Pure Bio-Active D-Mannose, vegetable magnesium stearate and hpmc film coating less than 0.1g. No artificial colourings, flavourings, or preservatives.


  • No nuts but cannot guarantee nut free.
  • Always consult a doctor if you have a health problem or considering taking any supplement with prescription drugs.
  • Always replace the lid tightly.
  • Use by Best Before End date.

Further Studies and Clinical Trials

The results indicate that D-mannose and D-glucose can significantly reduce bacteriuria within 1 day and that their efficacy is dependent upon the concentration of both saccharide and bacteria.
Michaels EK, Chmiel JS, Plotkin BJ, Schaeffer AJ. - Effect of D-mannose and D-glucose on Escherichia coli bacteriuria in rats.
Mannose and N-acetyl-D-galactosamine inhibited adhesion of E. coli and P. aeruginosa to epithelial cells, whereas only mannose inhibited adhesion of S. zooepidemicus. The other sugars did not affect bacterial adherence
King SS, Young DA, Nequin LG, Carnevale EM. - Use of specific sugars to inhibit bacterial adherence to equine endometrium in vitro.
D-Mannose is an essential glyconutrient for human health. As mentioned above, d-mannose is an important metabolic intermediate product in the biosynthesis of most secretory proteins and glycoproteins in the human body (Etchison and Freeze 1997). d-Mannose - specific transport systems have been identified that may function specifically to retain and utilize d-mannose. d-Mannose has been proven to have beneficial effects on the immune system (Newman 1994) and against metabolic syndrome (Pitkanen and others 1999), diabetes (Vuksan and others 1999), intestinal diseases (Ferket 2004), urinary tract infections (Altarac and Papeš 2014), and other diseases (Tizard and others 1988).
Xing Hu, Yaning Shi, Peng Zhang, Ming Miao, Tao Zhang, Bo Jiang - D-Mannose: Properties, Production, and Applications: An Overview - Benefits for human health
In a randomised controlled trial in women >18 years with acute UTI and a history of recurrent UTIs, three groups received either D Mannose daily for six months, nitrofurantoin prophylaxis for six months or nothing. The group receiving nothing had a higher rate of recurrence (60%) vs D-mannose (15%) vs nitrofurantoin (20%).
Dr Vikky Morris BSc MBBS FRCP, Musgrove Park Hospital, Taunton, Somerset - British Journal of Family Medicine, May/June 2015 Recurrent urinary tract infections - Non antimicrobial prevention

Frequently Asked Questions

Reveal All FAQs

Why is there so much confusion about D-Mannose doses?

One reason is because purity varies from manufacturer to manufacturer. Our D-Mannose is 100% contaminant free, pure bio-active D-Mannose.

What exactly is Waterfall D-Mannose ?

It is not a herbal product, but a monosaccharide isomer of glucose, a food supplement naturally produced without using solvents. We only use the best mannose available and produce a product that is 100% contaminant free.

What type of bladder and urinary tract support does Waterfall D-Mannose provide?

Waterfall D-Mannose supports a healthy bladder by providing bio-available mannose to the urine. People with a naturally healthy bladder usually have sufficient mannose in their urine. Some people may not have enough. Supplementing your diet with additional mannose is a natural way to help maintain a healthy bladder. We get hundreds of customers every month thanking us for Waterfall D-Mannose .

Are the Waterfall D-Mannose tablets as effective as the powder?

Yes. The only difference between the tablets and the powder is that the tablets have binding agents. And, of course, you just swallow the tablets with a drink instead of dissolving them in water. And they are just as good value. Waterfall D-Mannose tablets carry the unique Waterfall D-Mannose stamp. This is your guarantee of purity and safety with 1000mg of pure D Mannose powder in every tablet. Our new biodegradable packaging fits through the letter box. Our new flip top pocket-sized handy packs, chemical free and also biodegradable, ensure discretion and convenience when you are away from home.

Is Waterfall D-Mannose safe, even when taking large doses?

Yes, to the very best of our knowledge, and according to all research, D-Mannose is completely safe. Mannose is an essential glyconutrient, a food supplement rather than a medicine. It is already in every cell in your body, and your body produces mannose naturally, just as we produce vitamins like C and D. Mannose is also present in minute quantities in some foods like blueberries, pineapple, and Aloe Vera. Waterfall D-Mannose (we speak only for our product) has no known adverse effects at normal or even high consumption levels. Suggested maximum consumption is 1.76 ounces (50 grams) a day. Being a natural product rather than a medicine, you can decide how much to take. Our guidelines are flexible.

"In humans, no adverse effects have been noted when oral doses of approximately 15 grams were administered at a time (about 10 level teaspoons). Even oral doses as extreme as 53 grams per day given over an 11-month period showed no adverse side effects. However, when excessively large amounts (35 grams per hour) of Mannose was injected intravenously continuously for 10 hours, human subjects did experience fatigue, anorexia, malaise, and uric acid crystalluria.”

Any other sugar injected at these levels could kill, so it highlights safety rather than dangers.

If for some unknown reason you want to take such huge quantities of Waterfall D-Mannose intravenously, especially over an extended period, it would be best to discuss this with your doctor or an experienced nutritionist.

Our anecdotal experience since 2003 is that if you take more than about 3 times the suggested measure of Waterfall D-Mannose , you only absorb part of it through the small intestine. The remainder passes through to the large intestine, and could cause some wind and diarrhea.

Does Waterfall D-Mannose feed Candida?

Not in any way whatsoever. But it's not a treatment for Candida either. Candida (Candidiasis) or thrush is a fungal infection, of which Candida albicans is the most common. Candidiasis presents as oral thrush and vaginitis, right through to systemic and potentially life-threatening diseases. Candida infections of the latter category are also referred to as candidemia and are usually confined to severely immunocompromized persons, such as cancer, transplant, and AIDS patients as well as non-trauma emergency surgery patients.

In normally healthy people, Candida overgrowth is commonly associated with antibiotic therapy.


To help fight Candida A., we have seen that the following works:

  • Cut down on sugar and (white) carbohydrate intake.
  • Good quality probiotics are essential to provide friendly bacteria that compete with the fungal spores.
  • Take Coconut milk and cool with coconut oil, Caprylic acid and Lauric acid.
  • A little bicarb in a sitz bath is soothing as is natural yoghurt or coconut oil on the outside tissues.
  • Avoid sugar and simple carbohydrates.

What's a good way to determine how much Waterfall D-Mannose to take?

Everyone is different, so our information on our product suggests between 1 and 8 level teaspoons a day, or between 2 and 12 grams a day, depending on your individual requirements. When you have an infection, you must take one dose every three hours and wake up for a dose at least once during the night. You need to also keep the urine pH above 7.5. Please see a doctor if there is no improvement.

Is Waterfall D-Mannose safe for babies and pregnant mothers?

To the very best of our knowledge, Waterfall D-Mannose is safe for everyone. Pure D-mannose is an essential glyconutrient. Waterfall D Mannose is an isomer of glucose, not glucose, so is not metabolized. Your doctor or health care advisor will appreciate this fact. It is generally considered safer than white sugar, or drug therapy when pregnant. Although we have a lot of experience in this area, and knowledge of cystitis and related conditions, we are not medically qualified. We can't take account of individual circumstances, and advise that people should always consult their doctor before changing medical treatments, or starting on any alternative remedy or drug. Explaining the following will help you and your doctor make a decision:

  • Waterfall D-Mannose is an isomer of glucose, not glucose.
  • It is naturally manufactured without chemicals.
  • It is certified free of any contaminants.
  • It is already present already in every body cell.

Is Waterfall D-Mannose safe for Children?

To the very best of our knowledge, Waterfall D-Mannose is safe for everyone. We received this from a customer...

Dear Anna,

My daughter first got a urinary tract infection in March 2012 when she was four years old. The urinary infections caused terrible stomach pains, fever, vomiting and frequents rushes to the toilet. In the following year she was tested for infections no less than nine times and each time she was prescribed antibiotics. The antibiotics made her stomach upset and caused fatigue - walking to the corner shop was like trekking up a mountain for her.

Her attendance at school dropped significantly because she was often too ill to attend. Her urinary tract and kidneys were investigated for abnormalities but the doctors could find no reason for the repeated infections. The only suggestion for treatment that they had was low dosage antibiotics for six months. We tried all manner of preventative measures but nothing worked.

A year into this awful cycle of infections, antibiotics and visits to the pediatrician, my osteopath told me to try D-mannose. I waited a year before I tried it - in retrospect I wished I had tried it sooner as it would have saved my daughter a lot of pain and our family a lot of heartache. In June of 2014 we started with a dose of half a teaspoon in an inch of water once a day. My daughter has not had an infection since. It has taken her eight months to get her energy back but she is now an active, happy, infection-free seven year old.

D-mannose has changed our lives and we couldn’t be more grateful that we discovered it.



What if I get some adverse symptoms despite what you say?

At normal or even five times normal consumption levels, adverse side effects have not been reported, remember we produce a very pure, 100% contaminant free version. At very high consumption levels or after prolonged antibiotic use some wind and some loosening of the bowels may be noticed (poor absorption). If you have any concerns, please seek medical advice on your condition.

Can I take Waterfall D-Mannose even if I am taking a prescription drug?

There are no known drug interactions with Waterfall D-Mannose , although you should always ask your doctor before taking any alternative remedy alongside a prescription drug.

How can I use Waterfall D-Mannose to help support my bladder health around sex?

By taking the product around your sex and other triggers (such as sport, travelling etc.) you may help to support a healthy bladder. Taking an hour before and for up to 48 hours after major triggers has been shown to be a good preventative.

Will Waterfall D-Mannose stop me from becoming pregnant?

The short answer is no.

Can the product be used on animals?

Yes, we supply to vets for cats, dogs, and horses, because it works well for animals. The effect is dose related, so you have to give Waterfall D-Mannose proportionally according to the animal's weight. Please see our D-Mannose Pet product.

Do you always have large quantities of Waterfall D-Mannose in stock?


When will you dispatch my order?

Same day, Monday - Friday, for all orders placed before 5:30pm, by Free First Class post, Special Delivery, or Courier. We match the delivery to your needs. You can order Special Delivery up to 5:20pm, Monday to Friday.

I am a satisfied user of your product. Do you have any special offers?

Yes, there are always savings available when multiple units are bought. We also have offers in our news letters.

If I feel that I need to take a product that helps to support a healthy bladder, will my partner need to take it too?

Not usually. Stay clean, stay safe. Make a note of your triggers, and avoid them.

Try to keep urine alkaline. Don't take cranberry or orange juice, and if you take more than 100 - 150 mg of vitamin C, most of the excess goes straight into your urine, increasing urine acidity.

Should I take Waterfall D-Mannose before bed or during the night?

That's up to you and the level of support that you feel your bladder needs. A maintenance dose before sleep works well. During a flare up, you will need to wake up for a dose during the night or after urinating.

What other benefits could there be from taking Waterfall D-Mannose ?

Mannose is an essential glyconutrient, and by taking it, you are providing one of the foods that your body needs for optimum health, just as it needs a certain amount of vitamins, protein, etc. Long term customers find the freedom from bladder infections is a major benefit to their quality of life.

Will Waterfall D Mannose act as a contraceptive?

Since 2003 all of our experience and research, gives us no reason to believe that there is a contraceptive effect. So very many of our customers have told us they continued using it while trying to conceive, and throughout their subsequent pregnancy.

Sperm does attach to eggs in the same way that E. Coli attaches to body cells - using mannose receptors. So D-Mannose could in theory fill the sperm's mannose receptors and stop them from sticking to eggs.

However, this is a temporary effect since mannose is completely out of your system within 4 hours of ingestion.

There has been research on using D-Mannose as a natural contraceptive, perhaps with slow release implants, the only way to make it effective as a contraceptive. However, it seems unlikely that it will will ever work as a contraceptive, given as much as 90% of the d-mannose is passed through the kidneys within the first hour and it all leaves the body within four hours.

Other active ingredients or methods (as in implants) would be required to enable it to work as a contraceptive. When shipping to Austria, we are required to label the product with information stating that it cannot be used as a contraceptive. What we have always said is that if you are trying to get pregnant, it's probably best to avoid taking large quantities of d-mannose around sex, unless avoiding a UTI outweighs other needs.

Having said all that, sperm are not likely to encounter mannose on its way to the egg since you are taking it orally, not applying it topically... and in fact, it is used in animal insemination alongside semen to prevent infection without impeding conception.

Of course, conception does not occur during sexual intercourse - it happens up to 36 hours later, when you are likely to be doing something quite different and when the temporary effect, if any, will have disappeared completely...

We wish you success and health and sincerely hope that you have a happy and healthy pregnancy. Please refer any health concerns to a competent and caring medical practitioner who knows your personal history and current situation.

Should I be concerned that vegetable magnesium stearate is used in the tablet form of Waterfall D-Mannose ?

It has been pointed out that one-half bar of milk chocolate has approximately 1,283 mg of stearic acid. A half bar of chocolate, to give a comparison, has in fact 2000 times more than is found in one tablet of Waterfall D-Mannose .

What does the D in D-Mannose stand for?

The D in d-mannose does not refer to dextra, which means sugar. Although seeing the D in front of a product name does generally indicate that the product is a sugar, and generally a monosaccharide. However, D before mannose actually refers to the D orientation of the sugar molecule.

For example, in D-glucose and L-glucose, the D and L prefixes are used with monosaccharides, to differentiate stereoisomers that are mirror-images of each other.

In the Fischer projection the D and L prefixes specifies the configuration at the carbon atom that is second from bottom: D if the hydroxyl is on the right side, and L if it is on the left side.

In 1890, Fischer established the stereo chemical nature and isomeric properties of the sugars, and eventually established the stereo chemical configuration of all the known sugars.

Do you have another question you'd like to ask?

Please explore the rest of this website and feel free to use a search engine to find out more. If your question is not answered on this site, you are welcome to call us on +44 01904 789559 or fill in the form below.

Related Research

DMannose Clinical Trial -
NIH states: In our study, D-mannose powder had significantly reduced the risk of recurrent UTI

Urinary tract infections in women: a pilot study (PDF)

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